Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities | Zendy

Serkan Yavuz | Zendy; Hilal Yıldırım | Zendy

Open Access

Ferrocene Derivatives Carrying Urea, Thiourea, and Sulfonamide Moieties: Synthesis and Evaluation of Antibacterial and Antifungal Activities

Author(s) -

Serkan Yavuz,

Hilal Yıldırım

Publication year - 2013

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.436

H-Index - 50

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2013/149693

Subject(s) - chemistry , thiourea , sulfonamide , bacillus subtilis , antimicrobial , ferrocene , semicarbazone , candida albicans , klebsiella pneumonia , antibacterial activity , urea , minimum inhibitory concentration , gram positive bacteria , escherichia coli , bacteria , microbiology and biotechnology , organic chemistry , biochemistry , electrode , electrochemistry , biology , genetics , gene

In the present study, some novel ferrocene derivatives carrying urea, thiourea, and sulfonamide groups were synthesized, and all compounds were characterized by spectral and elemental analyses. These compounds were screened for their antibacterial activities and also their minimum inhibitory concentration (MIC) against Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) and Gram-negative bacteria (Klebsiella pneumonia and Escherichia coli) and antifungal activities against Saccharomyces cerevisiae and Candida albicans. Amongst the tested compounds, 4b, 4c, 5b, and 6b displayed excellent antimicrobial activity

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