Glossopharyngeal Dystonia Secondary to a Lurasidone-Fluoxetine CYP-3A4 Interaction | Zendy

Sean Paul | Zendy; Brian R. Cooke | Zendy; Mathew Nguyen | Zendy

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Glossopharyngeal Dystonia Secondary to a Lurasidone-Fluoxetine CYP-3A4 Interaction

Author(s) -

Sean Paul,

Brian R. Cooke,

Mathew Nguyen

Publication year - 2013

Publication title -

case reports in psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.17

H-Index - 4

eISSN - 2090-682X

pISSN - 2090-6838

DOI - 10.1155/2013/136194

Subject(s) - medicine , dystonia , fluoxetine , lurasidone , pharmacology , anesthesia , psychiatry , schizophrenia (object oriented programming) , antipsychotic , receptor , serotonin

Acute dystonic reactions are becoming much less prevalent in clinical practice due to the use of newer antipsychotics. Drug-drug interactions, patient characteristics, and environmental and genetic factors all contribute to the rate of occurrence of acute dystonia with second generation agents. In this case, we report a glossopharyngeal dystonia secondary to a lurasidone-fluoxetine CYP-3A4 interaction to highlight the importance of maintaining an index of suspicion for laryngeal dystonia, a potentially fatal dystonia.

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