Curcumin-Loaded Chitosan/Gelatin Composite Sponge for Wound Healing Application | Zendy

Van Cuong Nguyen | Zendy; Van Boi Nguyen | Zendy; MingFa Hsieh | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Curcumin-Loaded Chitosan/Gelatin Composite Sponge for Wound Healing Application

Author(s) -

Van Cuong Nguyen,

Van Boi Nguyen,

MingFa Hsieh

Publication year - 2013

Publication title -

international journal of polymer science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.399

H-Index - 33

eISSN - 1687-9430

pISSN - 1687-9422

DOI - 10.1155/2013/106570

Subject(s) - curcumin , gelatin , chitosan , wound healing , sponge , in vivo , materials science , composite number , gelatin sponge , chemistry , pharmacology , medicine , composite material , surgery , biochemistry , biology , microbiology and biotechnology , botany , embolization

Three composite sponges were made with 10% of curcumin and by using polymers, namely, chitosan and gelatin with various ratios. The chemical structure and morphology were evaluated by FTIR and SEM. These sponges were evaluated for water absorption capacity, antibacterial activity, in vitro drug release, and in vivo wound healing studies by excision wound model using rabbits. The in vivo study presented a greater wound closure in wounds treated with curcumin-composite sponge than those with composite sponge without curcumin and untreated group. These obtained results showed that combination of curcumin, chitosan and gelatin could improve the wound healing activity in comparison to chitosan, and gelatin without curcumin

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research