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Unilateral Hydronephrosis and Renal Damage after Acute Leukemia
Author(s) -
Egle Simanauskiene,
Valentina Daugelaviciene,
Arvydas Laurinavičius,
Ugnius Mickys,
Vaida Simonyte,
Goda Vaitkevičienė,
Gilvydas Verkauskas
Publication year - 2012
Publication title -
case reports in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.2
H-Index - 20
eISSN - 1687-9627
pISSN - 1687-9635
DOI - 10.1155/2012/968491
Subject(s) - medicine , hydronephrosis , asymptomatic , exacerbation , nephrectomy , kidney , radiology , urology , surgery , urinary system
A 14-year-old boy presented with asymptomatic right hydronephrosis detected on routine yearly ultrasound examination. Previously, he had at least two normal renal ultrasonograms, 4 years after remission of acute myeloblastic leukemia, treated by AML-BFM-93 protocol. A function of the right kidney and no damage on the left was confirmed by a DMSA scan. Right retroperitoneoscopic nephrectomy revealed 3 renal arteries with the lower pole artery lying on the pelviureteric junction. Histologically chronic tubulointerstitial nephritis was detected. In the pathogenesis of this severe unilateral renal damage, we suspect the exacerbation of deleterious effects of cytostatic therapy on kidneys with intermittent hydronephrosis.

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