Regioselective Syntheses of 3-Benzyl-Substituted 7H-Thiazolo[3,2-a]pyrimidine-7-ones through Palladium-Catalyzed Heteroannulation of Acetylenic Compounds | Zendy

Mohammad Bakherad | Zendy; Farzaneh Gholipoor | Zendy

Open Access

Regioselective Syntheses of 3-Benzyl-Substituted 7H-Thiazolo[3,2-a]pyrimidine-7-ones through Palladium-Catalyzed Heteroannulation of Acetylenic Compounds

Author(s) -

Mohammad Bakherad,

Farzaneh Gholipoor

Publication year - 2012

Publication title -

organic chemistry international

Language(s) - English

Resource type - Journals

eISSN - 2090-2018

pISSN - 2090-200X

DOI - 10.1155/2012/956584

Subject(s) - triethylamine , chemistry , regioselectivity , pyrimidine , palladium , acetonitrile , aryl , catalysis , base (topology) , medicinal chemistry , combinatorial chemistry , organic chemistry , stereochemistry , alkyl , mathematics , mathematical analysis

An efficient synthesis of 3-benzyl-substituted 7H-thiazolo[3,2-a]pyrimine-7-ones in acetonitrile is accomplished via Pd- and Cu-catalyzed reaction of 2-mercaptopropargylpyrimidone with various aryl iodides in the presence of triethylamine as the base

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