The Therapeutic Benefit of Allopurinol in the Treatment of Foreign Body Granulomas Caused by Polymethylmethacrylate Microspheres | Zendy

Luisa Kelmer Côrtes de Barros Silveira | Zendy; Felipe Ladeira de Oliveira | Zendy; Thais de Barros Castro Alves | Zendy; M Rambaldi | Zendy; Felipe Cupertino de Andrade | Zendy; Santuzza de Carvalho Kelmer | Zendy; Fábio Cuiabano Barbosa | Zendy

Open Access

The Therapeutic Benefit of Allopurinol in the Treatment of Foreign Body Granulomas Caused by Polymethylmethacrylate Microspheres

Author(s) -

Luisa Kelmer Côrtes de Barros Silveira,

Felipe Ladeira de Oliveira,

Thais de Barros Castro Alves,

M Rambaldi,

Felipe Cupertino de Andrade,

Santuzza de Carvalho Kelmer,

Fábio Cuiabano Barbosa

Publication year - 2012

Publication title -

case reports in dermatological medicine

Language(s) - English

Resource type - Journals

eISSN - 2090-6471

pISSN - 2090-6463

DOI - 10.1155/2012/945205

Subject(s) - microsphere , allopurinol , medicine , foreign body , foreign bodies , surgery , pathology , engineering , chemical engineering

Injectable polymethylmethacrylate (PMMA) microspheres are nonbiodegradable and too large for macrophage phagocytosis. There are several complications possible to happen, like chronic nonspecific inflammatory reactions, lip stiffness, infection, and granulomas. The occurrence of granulomas can lead to a not aesthetic result, making some extreme changes in the patient's life. The objective of this case report is to describe the successful treatment of foreign body granulomas caused by polymethylmethacrylate microspheres using allopurinol, an innovative therapy for this condition.

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