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Myocardial Dysfunction in Sepsis: A Large, Unsolved Puzzle
Author(s) -
Constantino José Fernandes,
Murillo Santucci César de Assunção
Publication year - 2012
Publication title -
critical care research and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 27
eISSN - 2090-1313
pISSN - 2090-1305
DOI - 10.1155/2012/896430
Subject(s) - medicine , sepsis , cardiac dysfunction , depression (economics) , intensive care medicine , pathophysiology , incidence (geometry) , cardiology , heart failure , physics , economics , optics , macroeconomics
Sepsis has high incidence and mortality rates around the world. The role of cardiac depression in myocardial dysfunction during sepsis remains to be elucidated. This review attempts to summarize our understanding of the anatomical, histopathological, and pathophysiological mechanisms behind cardiac dysfunction. Biomarkers to detect cardiac depression have been used to recognize developing problems, but the actual impact of these tools remains unclear.

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