Differences in the Treatment Response to Antithyroid Drugs versus Electroconvulsive Therapy in a Case of Recurrent Catatonia due to Graves’ Disease | Zendy

Takahiro Saito | Zendy; Rie Saito | Zendy; Hiroshi Suwa | Zendy; Fumiatsu Yakushiji | Zendy; Kenji Takezawa | Zendy; Mitsuru Nakamura | Zendy

Open Access

Differences in the Treatment Response to Antithyroid Drugs versus Electroconvulsive Therapy in a Case of Recurrent Catatonia due to Graves’ Disease

Author(s) -

Takahiro Saito,

Rie Saito,

Hiroshi Suwa,

Fumiatsu Yakushiji,

Kenji Takezawa,

Mitsuru Nakamura

Publication year - 2012

Publication title -

case reports in psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.17

H-Index - 4

eISSN - 2090-682X

pISSN - 2090-6838

DOI - 10.1155/2012/868490

Subject(s) - medicine , catatonia , electroconvulsive therapy , graves' disease , antithyroid drugs , disease , anxiolytic , thyroid function , pediatrics , thyroid , psychiatry , schizophrenia (object oriented programming) , anxiety

We reported a case which presented recurrent episodes of catatonia as a result of Graves' disease with hyperthyroidism. The patient showed different treatment response in each episodes; in the first episode, psychiatric and physical symptoms were resolved by a combination of antithyroid and anxiolytic therapies, while in the second episode, the combination therapy did not ameliorate her symptoms and ECT was indicated. We postulated that decreased CSF level of TTR and the resulting susceptibility to the derangement of peripheral thyroid function might be involved in this different treatment response.

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