The Effect of Alcohol on Postprandial and Fasting Triglycerides | Zendy

A. van de Wiel | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The Effect of Alcohol on Postprandial and Fasting Triglycerides

Author(s) -

A. van de Wiel

Publication year - 2011

Publication title -

international journal of vascular medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.411

H-Index - 27

eISSN - 2090-2832

pISSN - 2090-2824

DOI - 10.1155/2012/862504

Subject(s) - postprandial , chylomicron , hypertriglyceridemia , very low density lipoprotein , medicine , alcohol , endocrinology , lipoprotein lipase , obesity , triglyceride , alcohol consumption , pancreatitis , meal , diabetes mellitus , lipoprotein , adipose tissue , biochemistry , cholesterol , chemistry

Alcohol has a significant additive effect on the postprandial triglyceride peak when it accompanies a meal containing fat, especially saturated fat. This results from a decrease in the breakdown of chylomicrons and VLDL remnants due to an acute inhibitory effect of alcohol on lipoprotein lipase activity. Furthermore, alcohol increases the synthesis of large VLDL particles in the liver, which is the main source of triglycerides in the hypertriglyceridemia associated with chronic excessive alcohol intake. In case of chronic consumption, lipoprotein lipase activity seems to adapt itself. The effect of alcohol on adipose tissues is less clear. Sometimes, a severe hypertriglyceridemia induced by alcohol (SHIBA) can be observed, especially in patients with type 2 diabetes mellitus and/or obesity increasing the risk of pancreatitis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research