Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case | Zendy

Soukaina Regragui | Zendy; S. Amelal | Zendy; S. Astati | Zendy; M. Zine | Zendy; N. Alami Drideb | Zendy; A. Bouzidi | Zendy; N. Messaoudi | Zendy; Majid Benkirane | Zendy; Kamal Doghmi | Zendy; M. Mikdame | Zendy

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Thrombotic Microangiopathy with Skin Localization Secondary to Cytarabine-Daunorubicin Association: Report of a Case

Author(s) -

Soukaina Regragui,

S. Amelal,

S. Astati,

M. Zine,

N. Alami Drideb,

A. Bouzidi,

N. Messaoudi,

Majid Benkirane,

Kamal Doghmi,

M. Mikdame

Publication year - 2012

Publication title -

case reports in hematology

Language(s) - English

Resource type - Journals

eISSN - 2090-6560

pISSN - 2090-6579

DOI - 10.1155/2012/806476

Subject(s) - medicine , thrombotic thrombocytopenic purpura , thrombotic microangiopathy , cytarabine , leukemia , hemolytic anemia , gastroenterology , disease , platelet

The thrombotic microangiopathy is a syndrome characterized by the combination of mechanical hemolytic anemia, peripheral thrombocytopenia, and organ failure of variable severity. In addition to the idiopathic form, several cases are identified as secondary to pregnancy, infections, disease systems, organ transplants, and cancer. Other forms are secondary to drugs including antimitotics. We report the case of a patient followed for acute myelogenous leukemia. She received induction chemotherapy combining daunorubicin and cytarabine, complicated by thrombotic thrombocytopenic purpura.

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