Wine Polyphenols: Potential Agents in Neuroprotection
Author(s) -
Abdelkader Basli,
Stéphanie Soulet,
Nassima Chaher,
JeanMichel Mérillon,
Mohamed Chibane,
JeanPierre Monti,
Tristan Richard
Publication year - 2012
Publication title -
oxidative medicine and cellular longevity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.494
H-Index - 93
eISSN - 1942-0900
pISSN - 1942-0994
DOI - 10.1155/2012/805762
Subject(s) - neuroprotection , wine , polyphenol , oxidative stress , oxidative damage , antioxidant , health benefits , chemistry , pharmacology , traditional medicine , medicine , biochemistry , food science
There are numerous studies indicating that a moderate consumption of red wine provides certain health benefits, such as the protection against neurodegenerative diseases. This protective effect is most likely due to the presence of phenolic compounds in wine. Wine polyphenolic compounds are well known for the antioxidant properties. Oxidative stress is involved in many forms of cellular and molecular deterioration. This damage can lead to cell death and various neurodegenerative disorders, such as Parkinson’s or Alzheimer’s diseases. Extensive investigations have been undertaken to determine the neuroprotective effects of wine-related polyphenols. In this review we present the neuroprotective abilities of the major classes of wine-related polyphenols
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