Interleukin-4 receptor −3223C→T Polymorphism is Associated with Increased Gastric Adenocarcinoma Risk
Author(s) -
Florin Burada,
C Angelescu,
Paul Mitruț,
Tudorel Ciurea,
Mihai Cruce,
Adrian Săftoiu,
Mihai Ioana
Publication year - 2012
Publication title -
canadian journal of gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 1916-7237
pISSN - 0835-7900
DOI - 10.1155/2012/804173
Subject(s) - genotype , gastroenterology , medicine , adenocarcinoma , stomach cancer , allele , cancer , population , allele frequency , oncology , biology , genetics , gene , environmental health
Gastric cancer remains one of the most common types of cancer worldwide, with a large geographical variation in incidence and mortality rates. Cytokine polymorphisms are the most studied host polymorphisms and are associated with an increased risk of stomach cancer in many regions, but have not been studied extensively in Eastern European populations.
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