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Contrast-Enhanced Harmonic Endoscopic Ultrasonography in Pancreatic Diseases
Author(s) -
Can Xu,
Zhaoshen Li,
Michael B. Wallace
Publication year - 2012
Publication title -
diagnostic and therapeutic endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.158
H-Index - 24
eISSN - 1029-0516
pISSN - 1026-714X
DOI - 10.1155/2012/786239
Subject(s) - medicine , pancreas , differential diagnosis , endoscopic ultrasonography , radiology , perfusion , pathological , ultrasonography , microbubbles , second harmonic imaging microscopy , pancreatic mass , pancreatic tumor , pancreatic cancer , pathology , endoscopy , ultrasound , cancer , laser , physics , optics , second harmonic generation
Endoscopic ultrasonography (EUS) is the most sensitive imaging method for diagnosis of pancreatic tumors. However, it still has limits in the differentiation between pancreatic cancers and inflammatory tumor-like masses. A novel technology, contrast-enhanced harmonic EUS (CH-EUS), has been developed recently. It can visualize both parenchymal perfusion and microvasculature in pancreas without Doppler-related artifacts. Therefore, it is superior to EUS and CT in detecting small pancreatic masses and differential diagnosis of pancreatic masses. CH-EUS could be used for adequate sampling of pancreatic tumors and may predict the pathological features of the pancreatic solid lesions but still cannot replace EUS-FNA now.

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