A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain | Zendy

Yukiko Tabuchi | Zendy; Tetsuyuki Yasuda | Zendy; Hideaki Kaneto | Zendy; Tetsuhiro Kitamura | Zendy; Junji Kozawa | Zendy; Michio Otsuki | Zendy; Akihisa Imagawa | Zendy; Aya Nakae | Zendy; Youichi Matsuda | Zendy; H Uematsu | Zendy; Takashi Mashimo | Zendy; Masahiko Shibata | Zendy; Iichiro Shimomura | Zendy

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A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain

Author(s) -

Yukiko Tabuchi,

Tetsuyuki Yasuda,

Hideaki Kaneto,

Tetsuhiro Kitamura,

Junji Kozawa,

Michio Otsuki,

Akihisa Imagawa,

Aya Nakae,

Youichi Matsuda,

H Uematsu,

Takashi Mashimo,

Masahiko Shibata,

Iichiro Shimomura

Publication year - 2012

Publication title -

case reports in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.2

H-Index - 20

eISSN - 1687-9627

pISSN - 1687-9635

DOI - 10.1155/2012/740603

Subject(s) - hypogonadotropic hypogonadism , medicine , opioid , endocrine system , erectile dysfunction , chronic pain , magnetic resonance imaging , hormone , pediatrics , physical therapy , radiology , receptor

We report a case of 42-year-old male patient with hypogonadotropic hypogonadism. He suffered from general fatigue and erectile dysfunction after the treatment with transdermal fentanyl for chronic pain by traffic injury. Endocrine examinations and hormone stimulating tests showed that he had hypogonadotropic hypogonadism. Brain magnetic resonance imaging (MRI) showed no abnormal findings, and he had no past history of accounting for acquired hypogonadotropic hypogonadism. Therefore, his hypogonadism was diagnosed to be caused by opioid treatment. Although opioid-induced endocrine dysfunctions are not widely recognized, this case suggests that we should consider the possibility of endocrine dysfunctions in patients with opioid treatment.

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