RAS in Pregnancy and Preeclampsia and Eclampsia | Zendy

Macarena Rodríguez | Zendy; Jose Antonio Moreno-Sepulveda | Zendy; J Hasbún | Zendy

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RAS in Pregnancy and Preeclampsia and Eclampsia

Author(s) -

Macarena Rodríguez,

Jose Antonio Moreno-Sepulveda,

J Hasbún

Publication year - 2012

Publication title -

international journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.744

H-Index - 37

eISSN - 2090-0392

pISSN - 2090-0384

DOI - 10.1155/2012/739274

Subject(s) - preeclampsia , medicine , eclampsia , pregnancy , etiology , disease , endothelial dysfunction , bioinformatics , renin–angiotensin system , obstetrics , blood pressure , genetics , biology

Preeclampsia is a common disease of pregnancy characterized by the presence of hypertension and commitment of many organs, including the brain, secondary to generalized endothelial dysfunction. Its etiology is not known precisely, but it involved several factors, highlighting the renin angiotensin system (RAS), which would have an important role in the origin of multisystem involvement. This paper reviews the evidence supporting the involvement of RAS in triggering the disease, in addition to the components of this system that would be involved and how it eventually produces brain engagement.

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