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Objective . We examined personality traits in young women with FM, in order to seek associations with key psychological processes and clinical symptoms.  Methods . Twenty-seven women with FM and 29 age-matched female healthy controls [HC] completed a series of questionnaires examining FM symptoms, personality and psychological variables.  Results . Significant differences between characteristic FM symptoms (sleep, pain, fatigue, and confusion) as well as for the psychological variables of depression, anxiety, and stress were found between FM and HC ( P  < 0.001). Neuroticism was the only subscale of the Big Five Inventory that showed a significant difference between the FM group and HC group [ P  < 0.05]. Within the FM group, there was a significant association between the level of the neuroticism and each of pain, sleep, fatigue, and confusion, depression, anxiety, and stress ( P  < 0.05–0.01). The association between the level of neuroticism and the level of stress was the strongest of all variables tested ( P  < 0.001).  Conclusion . The personality trait of neuroticism significantly associates with the key FM characteristics of pain, sleep, fatigue and confusion as well as the common co-morbidities of depression, anxiety and stress. Personality appears to be an important modulator of FM clinical symptoms.

Neuroticism in Young Women with Fibromyalgia Links to Key Clinical Features