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The Management of Pregnancy in Women with Hepatocellular Adenoma: A Plea for an Individualized Approach
Author(s) -
Mirelle E. E. Bröker,
Jan N.M. IJzermans,
Susanna M. van Aalten,
Robert A. de Man,
Türkan Terkivatan
Publication year - 2012
Publication title -
international journal of hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 14
eISSN - 2090-3448
pISSN - 2090-3456
DOI - 10.1155/2012/725735
Subject(s) - medicine , pregnancy , hepatocellular adenoma , obstetrics , gynecology , adenoma , intensive care medicine , pediatrics , genetics , biology
Because of the risk of hormone-induced growth and spontaneous rupture of hepatocellular adenoma (HCA) during pregnancy, special considerations are required. Due to the scarcity of cases, there is no evidence-based algorithm for the evaluation and management of HCA during pregnancy. We think it should be questioned if it is justified to discourage pregnancy in all women with HCA. The biological behavior of this benign lesion might be less threatening than presumed and a negative advice concerning pregnancy has great impact on the lives of these young female patients. The balance between the pros and cons of hepatic adenomas and pregnancy should be reconsidered. In our center, pregnancy in women with an HCA up to 5 cm is no longer discouraged in close consultation with the patient, her partner, and members of the liver expert team.

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