Clinical Management of Acute Interstitial Pneumonia: A Case Report | Zendy

Yang Xia | Zendy; Zhenyu Liang | Zendy; Zhenzhen Fu | Zendy; Laiyu Liu | Zendy; Omkar Paudel | Zendy; Shaoxi Cai | Zendy

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Clinical Management of Acute Interstitial Pneumonia: A Case Report

Author(s) -

Yang Xia,

Zhenyu Liang,

Zhenzhen Fu,

Laiyu Liu,

Omkar Paudel,

Shaoxi Cai

Publication year - 2012

Publication title -

case reports in pulmonology

Language(s) - English

Resource type - Journals

eISSN - 2090-6846

pISSN - 2090-6854

DOI - 10.1155/2012/678249

Subject(s) - medicine , pulmonary edema , autopsy , lung , diffuse alveolar damage , mechanical ventilation , bronchiectasis , methylprednisolone , pneumonia , edema , pathology , anesthesia , surgery , acute respiratory distress

We describe a 51-year-old woman who was admitted to hospital because of cough and expectoration accompanied with general fatigue and progressive dyspnea. Chest HRCT scan showed areas of ground glass attenuation, consolidation, and traction bronchiectasis in bilateral bases of lungs. BAL fluid test and transbronchial lung biopsy failed to offer insightful evidence for diagnosis. She was clinically diagnosed with acute interstitial pneumonia (AIP). Treatment with mechanical ventilation and intravenous application of methylprednisolone (80 mg/day) showed poor clinical response and thus was followed by steroid pulse therapy (500 mg/day, 3 days). However, she died of respiratory dysfunction eventually. Autopsy showed diffuse alveolar damage associated with hyaline membrane formation, pulmonary interstitial, immature collagen edema, and focal type II pneumocyte hyperplasia.

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