Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone | Zendy

Anna Kotsia | Zendy; Georgios Dimitriadis | Zendy; Giannis Baltogiannis | Zendy; Theofilos M. Kolettis | Zendy

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Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone

Author(s) -

Anna Kotsia,

Georgios Dimitriadis,

Giannis Baltogiannis,

Theofilos M. Kolettis

Publication year - 2012

Publication title -

case reports in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.2

H-Index - 20

eISSN - 1687-9627

pISSN - 1687-9635

DOI - 10.1155/2012/673019

Subject(s) - amiodarone , medicine , qt interval , hypokalemia , prolongation , anesthesia , cardiology , long qt syndrome , atrial fibrillation

We report a case of torsade de pointes after intravenous amiodarone and concurrent hypokalemia. Despite treatment cessation and correction of electrolyte abnormalities, excessive QTc prolongation was noted, which persisted for 14 days. This prolonged course for QTc normalization may be attributed to the high rate of amiodarone loading and concurrent electrolyte disturbances coupled with possible underlying individual variability in pharmacokinetics.

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