Refractory Gout Attack | Zendy

Simone Fargetti | Zendy; Cláudia GoldensteinSchainberg | Zendy; Andressa Silva Abreu | Zendy; Ricardo Fuller | Zendy

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Refractory Gout Attack

Author(s) -

Simone Fargetti,

Cláudia GoldensteinSchainberg,

Andressa Silva Abreu,

Ricardo Fuller

Publication year - 2012

Publication title -

case reports in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.2

H-Index - 20

eISSN - 1687-9627

pISSN - 1687-9635

DOI - 10.1155/2012/657694

Subject(s) - gout , medicine , benzbromarone , febuxostat , uric acid , refractory (planetary science) , gouty arthritis , dermatology , hyperuricemia , physics , astrobiology

Refractory gout attack is an uncommon problem, since gout flares are usually self-limited. This clinical condition is characterized by serum uric acid higher than 6 mg/Dl or continuous manifestations of recurrent flares, chronic arthritis, and increased tophi. We report in this paper a 69-year-old man with a polyarticular and protracted gout attack, despite usual treatment and low urate sera levels. In order to manage this problem, we reviewed gout pathophysiology and developed a therapeutic solution based on benzbromarone pharmacokinetics. We also review herein new options for gout treatment that could be used in similar cases.

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