Notch Signaling during Oogenesis inDrosophila melanogaster | Zendy

Jingxia Xu | Zendy; Thomas Gridley | Zendy

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Notch Signaling during Oogenesis inDrosophila melanogaster

Author(s) -

Jingxia Xu,

Thomas Gridley

Publication year - 2012

Publication title -

genetics research international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.351

H-Index - 9

eISSN - 2090-3154

pISSN - 2090-3162

DOI - 10.1155/2012/648207

Subject(s) - drosophila melanogaster , oogenesis , microbiology and biotechnology , notch signaling pathway , drosophila (subgenus) , biology , signal transduction , genetics , oocyte , gene , embryo

The Notch signaling pathway is an evolutionarily conserved intercellular signaling mechanism that is required for embryonic development, cell fate specification, and stem cell maintenance. Discovered and studied initially in Drosophila melanogaster , the Notch pathway is conserved and functionally active throughout the animal kingdom. In this paper, we summarize the biochemical mechanisms of Notch signaling and describe its role in regulating one particular developmental pathway, oogenesis in Drosophila .

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