Agomelatine Augmentation of Escitalopram Therapy in Treatment-Resistant Obsessive-Compulsive Disorder: A Case Report | Zendy

Domenico De Berardis | Zendy; Nicola Serroni | Zendy; Stefano Marini | Zendy; Giovanni Martinotti | Zendy; Francesca Ferri | Zendy; G. Callista | Zendy; Raffaella La Rovere | Zendy; Francesco Saverio Moschetta | Zendy; Massimo Di Giannantonio | Zendy

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Agomelatine Augmentation of Escitalopram Therapy in Treatment-Resistant Obsessive-Compulsive Disorder: A Case Report

Author(s) -

Domenico De Berardis,

Nicola Serroni,

Stefano Marini,

Giovanni Martinotti,

Francesca Ferri,

G. Callista,

Raffaella La Rovere,

Francesco Saverio Moschetta,

Massimo Di Giannantonio

Publication year - 2012

Publication title -

case reports in psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.17

H-Index - 4

eISSN - 2090-682X

pISSN - 2090-6838

DOI - 10.1155/2012/642752

Subject(s) - escitalopram , agomelatine , medicine , obsessive compulsive , antidepressant , psychiatry , distress , major depressive disorder , aripiprazole , clinical psychology , anxiety , mood , schizophrenia (object oriented programming)

Obsessive-compulsive disorder (OCD) is a chronic condition characterized by obsessions or compulsions that cause distress or interfere with functioning. Selective serotonin reuptake inhibitors are the first-line strategy in the treatment of OCD, but approximately 40% to 60% of patients with OCD fail to respond to them. Several augmentation strategies have been proposed, including the use of atypical antipsychotics and antidepressant combinations. In the present paper we describe the case of a young female patient suffering from severe treatment-resistant OCD who remitted as a result of agomelatine augmentation of escitalopram therapy.

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