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Gestational Diabetes Insipidus Associated with HELLP Syndrome: A Case Report
Author(s) -
Renela Gambito,
Michael E Chan,
Mohamed Sheta,
Precious Ramirez-Arao,
Harmeet Gurm,
Allan R. Tunkel,
Noel Nivera
Publication year - 2012
Publication title -
case reports in nephrology
Language(s) - English
Resource type - Journals
eISSN - 2090-6641
pISSN - 2090-665X
DOI - 10.1155/2012/640365
Subject(s) - medicine , hellp syndrome , gestational diabetes , diabetes insipidus , preeclampsia , pregnancy , obstetrics , hypernatremia , complication , gestation , diabetes mellitus , endocrinology , pediatrics , chemistry , genetics , organic chemistry , biology , sodium
Gestational diabetes insipidus is a rare, but well recognized, complication of pregnancy. It is related to excess vasopressinase enzyme activity which is metabolized in the liver. A high index of suspicion of gestational diabetes insipidus is required in a correct clinical setting especially in the presence of other risk factors such as preeclampsia, HELLP syndrome, and twin pregnancies. We are presenting a case of gestational diabetes insipidus in a patient with HELLP syndrome. The newborn in this case also had hypernatremia thereby raising possibilities of vasopressinase crossing the placenta.

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