Open AccessKinetic Determination of Paracetamol using a Novel Belousov-Zhabotinskii Oscillating System Catalyzed by a Tetraazamacrocyclic Complex
Author(s) -
Guang Hu,
Qin Wang,
Min Meng,
M. Lu,
Fu Sheng Zhao,
Lin Hu
Publication year - 2011
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2012/626982
Subject(s) - catalysis , logarithm , perturbation (astronomy) , chemistry , briggs–rauscher reaction , oscillation (cell signaling) , amplitude , substrate (aquarium) , belousov–zhabotinsky reaction , kinetic energy , diene , malic acid , analytical chemistry (journal) , stereochemistry , thermodynamics , chromatography , physics , mathematical analysis , organic chemistry , mathematics , classical mechanics , quantum mechanics , biochemistry , oceanography , geology , natural rubber , citric acid
A new analytical method for determination of paracetamol is proposed. This method is based on a novel B-Z oscillating system, which involves a Tetraazamacrocyclic Complex [CuL](ClO4)2 as catalyst and malic acid as the substrate. The ligand L in the complex is 5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradeca-4,11-diene. By perturbation mount of paracetamol on the B-Z system, there is a linear relationship between the changes in the oscillation amplitude and the logarithm of paracetamol concentration in the range 5×10-7 to 2×10-4 M, with a correlation coefficient of 0.99743. The effects of influential variables, such as the concentration of reaction components, temperature and on the determinations were studied. The probable mechanism involving the perturbation of paracetamol on the oscillating chemical system was also discussed
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