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Background/aims : The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC).   Methods : 98 AIDS patients (25 with TRC, 43 with anti- T . gondii antibodies but without TCR, and 30 without anti- T . gondii antibodies and without TCR) were studied.   Results : The HLA-B35 was significantly increased in TRC group ( p = 0.0038).   Conclusion : The presence of HLA-B35 may simultaneously predispose to progression to AIDS and TRC.

Susceptibility to Toxoplasmic Retinochoroiditis Is Associated with Hla Alleles Reported to Be Implicated with Rapid Progression to Aids