Hypolipidemic Activity ofEryngium carlinaeon Streptozotocin-Induced Diabetic Rats | Zendy

Ruth NoriegaCisneros | Zendy; Omar OrtizAvila | Zendy; Edgar EsquivelGutiérrez | Zendy; Mónica ClementeGuerrero | Zendy; Salvador ManzoÁvalos | Zendy; Rafael SalgadoGarciglia | Zendy; Christian CortésRojo | Zendy; István Boldogh | Zendy; Alfredo SaavedraMolina | Zendy

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Hypolipidemic Activity ofEryngium carlinaeon Streptozotocin-Induced Diabetic Rats

Author(s) -

Ruth NoriegaCisneros,

Omar OrtizAvila,

Edgar EsquivelGutiérrez,

Mónica ClementeGuerrero,

Salvador ManzoÁvalos,

Rafael SalgadoGarciglia,

Christian CortésRojo,

István Boldogh,

Alfredo SaavedraMolina

Publication year - 2011

Publication title -

biochemistry research international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.631

H-Index - 36

eISSN - 2090-2255

pISSN - 2090-2247

DOI - 10.1155/2012/603501

Subject(s) - diabetes mellitus , hyperlipidemia , creatinine , medicine , streptozotocin , uric acid , cholesterol , endocrinology , lipid profile , traditional medicine

Diabetes mellitus (DM) is a significant risk factor for the development of cardiovascular complications. This study was undertaken to investigate the effect of chronic administration of ethanolic extract of Eryngium carlinae on glucose, creatinine, uric acid, total cholesterol, and triglycerides levels in serum of streptozotocin- (STZ-) induced diabetic rats. Triglycerides, total cholesterol, and uric acid levels increased in serum from diabetic rats. The treatment with E. carlinae prevented these changes. The administration of E. carlinae extract reduced the levels of creatinine, uric acid, total cholesterol, and triglycerides. Thus administration of E. carlinae is able to reduce hyperlipidemia related to the cardiovascular risk in diabetes mellitus.

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