The Role of Cytokines and Inflammatory Cells in Perinatal Brain Injury | Zendy

Ryan M. McAdams | Zendy; Sandra E. Juul | Zendy

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The Role of Cytokines and Inflammatory Cells in Perinatal Brain Injury

Author(s) -

Ryan M. McAdams,

Sandra E. Juul

Publication year - 2012

Publication title -

neurology research international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.365

H-Index - 31

eISSN - 2090-1852

pISSN - 2090-1860

DOI - 10.1155/2012/561494

Subject(s) - medicine , cytokine , proinflammatory cytokine , inflammation , brain damage , immunology , traumatic brain injury , psychiatry

Perinatal brain injury frequently complicates preterm birth and leads to significant long-term morbidity. Cytokines and inflammatory cells are mediators in the common pathways associated with perinatal brain injury induced by a variety of insults, such as hypoxic-ischemic injury, reperfusion injury, toxin-mediated injury, and infection. This paper examines our current knowledge regarding cytokine-related perinatal brain injury and specifically discusses strategies for attenuating cytokine-mediated brain damage.

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