A Caenorhabditis elegans Host Model Correlates with Invasive Disease Caused by Staphylococcus aureus Recovered during an Outbreak in Neonatal Intensive Care
Author(s) -
Kaiyu Wu,
Andrew E. Simor,
Mary Vearncombe,
JoAnn McClure,
Kunyan Zhang
Publication year - 2012
Publication title -
canadian journal of infectious diseases and medical microbiology
Language(s) - English
Resource type - Journals
eISSN - 1918-1493
pISSN - 1712-9532
DOI - 10.1155/2012/543817
Subject(s) - outbreak , caenorhabditis elegans , staphylococcus aureus , host (biology) , biology , microbiology and biotechnology , disease , virology , medicine , bacteria , genetics , gene
Caenorhabditis elegans has previously been used as a host model to determine the virulence of clinical methicillin-resistant Staphylococcus aureus isolates. In the present study, methicillin-susceptible S aureus (MSSA) strains associated with an outbreak in a neonatal intensive care unit (NICU) were investigated using the C elegans model.
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