Penicillin Susceptibility and Macrolide-Lincosamide-Streptogramin B Resistance in Group BStreptococcusIsolates from a Canadian Hospital | Zendy

Kevin Sherman | Zendy; Sue Whitehead | Zendy; Edith Blondel-Hill | Zendy; Ken Wagner | Zendy; Naowarat Cheeptham | Zendy

Open Access

Penicillin Susceptibility and Macrolide-Lincosamide-Streptogramin B Resistance in Group BStreptococcusIsolates from a Canadian Hospital

Author(s) -

Kevin Sherman,

Sue Whitehead,

Edith Blondel-Hill,

Ken Wagner,

Naowarat Cheeptham

Publication year - 2012

Publication title -

canadian journal of infectious diseases and medical microbiology

Language(s) - English

Resource type - Journals

eISSN - 1918-1493

pISSN - 1712-9532

DOI - 10.1155/2012/540127

Subject(s) - clindamycin , erythromycin , penicillin , microbiology and biotechnology , antibiotics , population , medicine , antibiotic resistance , biology , environmental health

Intrapartum antibiotic prophylaxis (IAP) is recommended for pregnant women who test positive for group B Streptococcus (GBS) in their genitourinary tract to prevent GBS-induced neonatal sepsis. Penicillin G is used as the primary antibiotic, and clindamycin or erythromycin as the secondary, if allergies exist. Decreased susceptibility to penicillin G has occasionally been reported; however, clindamycin and erythromycin resistance is on the rise and is causing concern over the use of clindamycin and erythromycin IAP.

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