Budding of Enveloped Viruses: Interferon-Induced ISG15—Antivirus Mechanisms Targeting the Release Process
Author(s) -
Eun Joo Seo,
Jonathan Leis
Publication year - 2012
Publication title -
advances in virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 25
eISSN - 1687-8647
pISSN - 1687-8639
DOI - 10.1155/2012/532723
Subject(s) - budding , isg15 , virology , biology , viral envelope , viral replication , interferon , innate immune system , virus , microbiology and biotechnology , immunology , genetics , immune system , ubiquitin , gene
Pathogenic strains of viruses that infect humans are encapsulated in membranes derived from the host cell in which they infect. After replication, these viruses are released by a budding process that requires cell/viral membrane scission. As such, this represents a natural target for innate immunity mechanisms to interdict enveloped virus spread and recent advances in this field will be the subject of this paper.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom