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Budding of Enveloped Viruses: Interferon-Induced ISG15—Antivirus Mechanisms Targeting the Release Process
Author(s) -
Eun Joo Seo,
Jonathan Leis
Publication year - 2012
Publication title -
advances in virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 25
eISSN - 1687-8647
pISSN - 1687-8639
DOI - 10.1155/2012/532723
Subject(s) - budding , isg15 , virology , biology , viral envelope , viral replication , interferon , innate immune system , virus , microbiology and biotechnology , immunology , genetics , immune system , ubiquitin , gene
Pathogenic strains of viruses that infect humans are encapsulated in membranes derived from the host cell in which they infect. After replication, these viruses are released by a budding process that requires cell/viral membrane scission. As such, this represents a natural target for innate immunity mechanisms to interdict enveloped virus spread and recent advances in this field will be the subject of this paper.

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