The Fetal Origins of the Metabolic Syndrome: Can We Intervene? | Zendy

Noelle Ma | Zendy; Daniel B. Hardy | Zendy

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The Fetal Origins of the Metabolic Syndrome: Can We Intervene?

Author(s) -

Noelle Ma,

Daniel B. Hardy

Publication year - 2012

Publication title -

journal of pregnancy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.828

H-Index - 32

eISSN - 2090-2735

pISSN - 2090-2727

DOI - 10.1155/2012/482690

Subject(s) - medicine , fetal programming , fetus , metabolic syndrome , in utero , etiology , pregnancy , incidence (geometry) , epidemiology , risk factor , intervention (counseling) , intensive care medicine , bioinformatics , obesity , endocrinology , psychiatry , genetics , physics , optics , biology

Epidemiological studies have suggested that metabolic programming begins during fetal life and adverse events in utero are a critical factor in the etiology of chronic diseases and overall health. While the underlying molecular mechanisms linking impaired fetal development to these adult diseases are being elucidated, little is known about how we can intervene early in life to diminish the incidence and severity of these long-term diseases. This paper highlights the latest clinical and pharmaceutical studies addressing how dietary intervention in fetal and neonatal life may be able to prevent aspects of the metabolic syndrome associated with IUGR pregnancies.

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