Open AccessSynthesis and Analgesic Studies of Some New 2‐pyrazolines
Author(s) -
S. Sridhar,
Y. Rajendraprasad
Publication year - 2011
Publication title -
journal of chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-9063
pISSN - 2090-9071
DOI - 10.1155/2012/476989
Subject(s) - analgesic , medicine , pharmacology
A new series of 2-pyrazolines (4a-j) were synthesized by reacting chalcones (3a-j) with phenyl hydrazine in the presence of pyridine and ethanol. All these compounds were characterized by means of their IR, 1H-NMR spectral data and microanalyses. When these compounds were evaluated for analgesic activity, some of them were found to possess significant activity, when compared to standard drugs
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