Assessing the Effects of Estrogen on the Dynamics of Breast Cancer | Zendy

Chipo Mufudza | Zendy; Walter Sorofa | Zendy; Edward T. Chiyaka | Zendy

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Assessing the Effects of Estrogen on the Dynamics of Breast Cancer

Author(s) -

Chipo Mufudza,

Walter Sorofa,

Edward T. Chiyaka

Publication year - 2012

Publication title -

computational and mathematical methods in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.462

H-Index - 48

eISSN - 1748-6718

pISSN - 1748-670X

DOI - 10.1155/2012/473572

Subject(s) - breast cancer , estrogen , disease , cancer , immune system , population , dynamics (music) , medicine , oncology , immunology , psychology , pedagogy , environmental health

Worldwide, breast cancer has become the second most common cancer in women. The disease has currently been named the most deadly cancer in women but little is known on what causes the disease. We present the effects of estrogen as a risk factor on the dynamics of breast cancer. We develop a deterministic mathematical model showing general dynamics of breast cancer with immune response. This is a four-population model that includes tumor cells, host cells, immune cells, and estrogen. The effects of estrogen are then incorporated in the model. The results show that the presence of extra estrogen increases the risk of developing breast cancer.

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