Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects | Zendy

Marco Mele | Zendy; Tinne Laurberg | Zendy; Tine Engberg Damsgaard | Zendy; Jonas Amstrup Funder | Zendy; Vibeke Jensen | Zendy

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Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects

Author(s) -

Marco Mele,

Tinne Laurberg,

Tine Engberg Damsgaard,

Jonas Amstrup Funder,

Vibeke Jensen

Publication year - 2012

Publication title -

case reports in pathology

Language(s) - English

Resource type - Journals

eISSN - 2090-6781

pISSN - 2090-679X

DOI - 10.1155/2012/427628

Subject(s) - medicine , pathological , melanocyte , pathology , pathogenesis , basement membrane , breast carcinoma , breast cancer , melanoma , colonization , cancer , biology , cancer research , microbiology and biotechnology

. Melanocyte colonization of breast carcinoma by nonneoplastic melanocytes of epidermal origin is a rare and serious condition first described in 1977. We report on the exceptional clinical and pathological features of this migration phenomenon in a 74-year-old patient. Discussion . The pathogenesis by which melanocyte migration takes place is not known, but a breached basement membrane is considered essential. Conclusion . Histological examination and additional staining of skin are essential to differentiate breast cancer melanosis from malignant melanoma.

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