English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background . An increasing resistance of  Helicobacter pylori  strains to antimicrobial agents is the serious therapeutic problem. The aim of this study was to compare the primary and secondary resistance of  H. pylori  strains isolated between 2006–2008 (data published) and 2009–2011 to clarithromycin and levofloxacin.  Material and Methods . 220 dyspeptic patients (153 before treatment, 67 after), were enrolled in the study. 51  H. pylori  strains were isolated. MIC values of clarithromycin and levofloxacin were determined by the  E -test method. The statistical analysis was conducted with the  χ   2  test with Yates correction at the 0.05 significance level ( P  ≤ 0.05).  Results . Between 2006 and 2008, 34% (39/115) of  H. pylori  strains were resistant to clarithromycin (primary 21% (19/90), secondary 80% (20/25)). 5% (6/115) of strains were resistant to levofloxacin (primary 2% (2/90), secondary 16% ((4/25); data published) Between 2009–2011, 22% (11/51) of  H. pylori  strains were resistant to clarithromycin (primary 19% (8/43), secondary 38% (3/8)). 16% (8/51) of strains were resistant to levofloxacin (primary 12% (5/43), secondary 38% (3/8)).  Conclusion . The present study has shown the increasing amount of resistant  H. pylori  strains isolated from patients in Southern Poland to levofloxacin and decreasing number of resistant strains to clarithromycin.

Variability in Prevalence ofHelicobacter pyloriStrains Resistant to Clarithromycin and Levofloxacin in Southern Poland