Macrophage Migration Inhibitory Factor in Protozoan Infections | Zendy

Marcelo T. Bozza | Zendy; Yuri Chaves Martins | Zendy; Letícia A. M. Carneiro | Zendy; Cláudia N. Paiva | Zendy

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Macrophage Migration Inhibitory Factor in Protozoan Infections

Author(s) -

Marcelo T. Bozza,

Yuri Chaves Martins,

Letícia A. M. Carneiro,

Cláudia N. Paiva

Publication year - 2012

Publication title -

journal of parasitology research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.46

H-Index - 27

eISSN - 2090-0031

pISSN - 2090-0023

DOI - 10.1155/2012/413052

Subject(s) - macrophage migration inhibitory factor , protozoan parasite , immune system , inflammation , immunology , macrophage , cytokine , protozoan infection , parasite hosting , biology , medicine , in vitro , computer science , biochemistry , world wide web

Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a general trend, MIF participates in the control of parasite burden at the expense of promoting tissue damage due to increased inflammation.

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