Synthesis, Isolation and Characterization of Process-Related Impurities in Oseltamivir Phosphate | Zendy

Yogesh Sharma | Zendy; Dau D. Agarwal | Zendy; Sudesh Bhure | Zendy; Sanjay Singh Rathore | Zendy; Chakravir Rawat | Zendy; Rajendranath Mukharjee | Zendy

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Synthesis, Isolation and Characterization of Process-Related Impurities in Oseltamivir Phosphate

Author(s) -

Yogesh Sharma,

Dau D. Agarwal,

Sudesh Bhure,

Sanjay Singh Rathore,

Chakravir Rawat,

Rajendranath Mukharjee

Publication year - 2011

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2012/327351

Subject(s) - isolation (microbiology) , characterization (materials science) , impurity , phosphate , oseltamivir , process (computing) , chemistry , materials science , biochemistry , nanotechnology , computer science , microbiology and biotechnology , medicine , organic chemistry , biology , covid-19 , disease , infectious disease (medical specialty) , operating system

Three known impurities in oseltamivir phosphate bulk drug at level 0.1% (ranging from 0.05-0.1%) were detected by gradient reverse phase high performance liquid chromatography. These impurities were preliminarily identified by the mass number of the impurities. Different experiments were conducted and finally the known impurities were synthesized and characterized

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