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Gastrointestinal Stromal Tumor in the Cecum of a Horse
Author(s) -
Sarah Stephan,
Sven E. Hug,
M. Hilbe
Publication year - 2012
Publication title -
case reports in veterinary medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.167
H-Index - 4
eISSN - 2090-701X
pISSN - 2090-7001
DOI - 10.1155/2012/301498
Subject(s) - cd117 , interstitial cell of cajal , gist , cd34 , stromal cell , gastrointestinal tract , cecum , pathology , immunohistochemistry , stromal tumor , medicine , mesenchymal stem cell , progenitor cell , biology , stem cell , genetics
Gastrointestinal stromal tumors (GISTs) are defined as specific CD117-(Kit, stem cell factor receptor) expressing tumors of the gastrointestinal (GI) tract. They are believed to originate from the interstitial pacemaker cells of Cajal (ICC) or their progenitor cells. In horses only a few cases of GISTs are described in the literature. In the present paper the macroscopical, histological, immunohistochemical, and ultrastructural features of an equine cecal GIST are described

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