Synthesis and Reactions of 3-(2-Chloromethyl-carbonylamino)tetrachloroquinazolin-2,4-dione
Author(s) -
M. A. HASSAN,
Ahmed Mohamed Mosalem Younes,
M. M. Taha,
Aboubakr H. Abdelmonsef
Publication year - 2012
Publication title -
organic chemistry international
Language(s) - English
Resource type - Journals
eISSN - 2090-2018
pISSN - 2090-200X
DOI - 10.1155/2012/284947
Subject(s) - bacillus cereus , salmonella typhi , chemistry , staphylococcus aureus , antibacterial activity , salmonella , in vitro , combinatorial chemistry , stereochemistry , bacteria , escherichia coli , biochemistry , biology , genetics , gene
A series of tetrachloroquinazolin-2,4-dione derivatives were synthesized using appropriate synthetic route and characterized by IR, 1H NMR, MS, and elemental analysis. The synthesized compounds were evaluated for their preliminary in vitro antibacterial activity towards Salmonella typhi, Staphylococcus aureus, and Bacillus cereus
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