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Flow Injection/Sequential Injection Analysis Systems: Potential Use as Tools for Rapid Liver Diseases Biomarker Study
Author(s) -
Supaporn Kradtap Hartwell
Publication year - 2012
Publication title -
international journal of hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.734
H-Index - 14
eISSN - 2090-3448
pISSN - 2090-3456
DOI - 10.1155/2012/281807
Subject(s) - instrumentation (computer programming) , biomarker , flow injection analysis , computer science , analyte , medicine , biochemical engineering , process engineering , chromatography , detection limit , engineering , chemistry , biochemistry , operating system
Flow injection/sequential injection analysis (FIA/SIA) systems are suitable for carrying out automatic wet chemical/biochemical reactions with reduced volume and time consumption. Various parts of the system such as pump, valve, and reactor may be built or adapted from available materials. Therefore the systems can be at lower cost as compared to other instrumentation-based analysis systems. Their applications for determination of biomarkers for liver diseases have been demonstrated in various formats of operation but only a few and limited types of biomarkers have been used as model analytes. This paper summarizes these applications for different types of reactions as a guide for using flow-based systems in more biomarker and/or multibiomarker studies.

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