Lymphoepithelioma-Like Carcinoma of the Skin Treated with Wide Local Excision and Chemoradiation Therapy: A Case Report and Review of the Literature | Zendy

Theresa Gille | Zendy; Edward F. Miles | Zendy; Allen O. Mitchell | Zendy

Open Access

Lymphoepithelioma-Like Carcinoma of the Skin Treated with Wide Local Excision and Chemoradiation Therapy: A Case Report and Review of the Literature

Author(s) -

Theresa Gille,

Edward F. Miles,

Allen O. Mitchell

Publication year - 2012

Publication title -

case reports in oncological medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.173

H-Index - 7

eISSN - 2090-6714

pISSN - 2090-6706

DOI - 10.1155/2012/241816

Subject(s) - medicine , lymphoepithelioma , lymphoepithelioma like carcinoma , nasopharyngeal carcinoma , surgical excision , perineural invasion , dermatology , wide local excision , radiation therapy , surgery , cancer , virus , virology , epstein–barr virus

Lymphoepithelioma-like carcinoma of the skin (LELCS) is a rare cutaneous neoplasm microscopically similar to undifferentiated nasopharyngeal carcinoma. It is typically nonaggressive and is treated with wide local excision. However, we present a case of a patient with a regional recurrence and more aggressive LELCS with perineural invasion and positive margins for which he was treated with wide local excision followed by chemoradiation. We discuss the use of chemoradiation for this patient and review the literature, specifically pertaining to treatment of more aggressive cases of LELCS.

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