Cell Proliferation Tracking Using Graphene Sensor Arrays | Zendy

Ronan Daly | Zendy; Shishir Kumar | Zendy; Gergely L. Lukács | Zendy; Kangho Lee | Zendy; Anne Weidlich | Zendy; Martin Hegner | Zendy; Georg S. Duesberg | Zendy

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Cell Proliferation Tracking Using Graphene Sensor Arrays

Author(s) -

Ronan Daly,

Shishir Kumar,

Gergely L. Lukács,

Kangho Lee,

Anne Weidlich,

Martin Hegner,

Georg S. Duesberg

Publication year - 2011

Publication title -

journal of sensors

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.399

H-Index - 43

eISSN - 1687-7268

pISSN - 1687-725X

DOI - 10.1155/2012/219485

Subject(s) - microfabrication , graphene , materials science , fabrication , nanotechnology , scalability , computer science , medicine , alternative medicine , pathology , database

The development of a novel label-free graphene sensor array is presented. Detection is based on modification of graphene FET devices and specifically monitoring the change in composition of the nutritive components in culturing medium. Micro-dispensing of Escherichia coli in medium shows feasibility of accurate positioning over each sensor while still allowing cell proliferation. Graphene FET device fabrication, sample dosing, and initial electrical characterisation have been completed and show a promising approach to reducing the sample size and lead time for diagnostic and drug development protocols through a label-free and reusable sensor array fabricated with standard and scalable microfabrication technologies

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