CdTe Quantum dots Modified by Polyamidoamine Dendrimers for Cell Imaging | Zendy

Jun’an Liu | Zendy; Xiaolei Wei | Zendy; Jianhua Cao | Zendy; Hong Jiang | Zendy

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CdTe Quantum dots Modified by Polyamidoamine Dendrimers for Cell Imaging

Author(s) -

Jun’an Liu,

Xiaolei Wei,

Jianhua Cao,

Hong Jiang

Publication year - 2011

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2012/195897

Subject(s) - quantum dot , biocompatibility , cadmium telluride photovoltaics , cytotoxicity , nanocomposite , nanotechnology , dendrimer , covalent bond , materials science , chemistry , in vitro , polymer chemistry , organic chemistry , biochemistry , metallurgy

Water soluble CdTe quantum dots have shown potential as a platform for development of live cell imaging, but their cytotoxicity limits their biological applications. To decrease their cytotoxicity, an approach to modify CdTe quantum dots (QDs) with polyamidoamine (PAMAM) was employed by forming covalent bonds between them. The resultant nanocomposites as a cell imaging bioprobe for live PK15 and their in vitro toxicity were also investigated. The results showed that the prepared nanocomposites were able to enter PK15 cells with good biocompatibility and low cellular toxicity

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