Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline | Zendy

R. H. Parab | Zendy; Bharat C. Dixit | Zendy

Open Access

Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline

Author(s) -

R. H. Parab,

Bharat C. Dixit

Publication year - 2011

Publication title -

journal of chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-9063

pISSN - 2090-9071

DOI - 10.1155/2012/164235

Subject(s) - imidazole , antimicrobial , chemistry , characterization (materials science) , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry , nanotechnology , materials science

A series of oxazole and thereof imidazole derivatives were prepared from 2-chloro-7-methyl-3-formyl quinoline. The structures of all synthesized compounds were elucidated by elemental, IR, 1HNMR, 13CNMR spectra. Supplementary to these, they were assayed in vitro for their antimicrobial activity; it was revealed that some synthesized derivatives were exhibiting competent biological activity against both gram negative and gram positive bacterial species and fungal microorganisms

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