Cell Signals Influencing Hepatic Fibrosis | Zendy

Min Cong | Zendy; Keiko Iwaisako | Zendy; Chunyan Jiang | Zendy; Tatiana Kisseleva | Zendy

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Cell Signals Influencing Hepatic Fibrosis

Author(s) -

Min Cong,

Keiko Iwaisako,

Chunyan Jiang,

Tatiana Kisseleva

Publication year - 2012

Publication title -

international journal of hepatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.734

H-Index - 14

eISSN - 2090-3448

pISSN - 2090-3456

DOI - 10.1155/2012/158547

Subject(s) - liver fibrosis , medicine , fibrosis , signal transduction , hepatic fibrosis , cell type , intracellular , pathophysiology , cell , cell signaling , liver cell , bioinformatics , pathology , cancer research , microbiology and biotechnology , biology , biochemistry

Liver fibrosis is the result of the entire organism responding to a chronic injury. Every cell type in the liver contributes to the fibrosis. This paper first discusses key intracellular signaling pathways that are induced during liver fibrosis. The paper then examines the effects of these signaling pathways on the major cell types in the liver. This will provide insights into the molecular pathophysiology of liver fibrosis and should identify therapeutic targets.

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