Chemokines and Chemokine Receptors in Susceptibility to HIV-1 Infection and Progression to AIDS | Zendy

Animesh Chatterjee | Zendy; Anurag S. Rathore | Zendy; Sanjukta Vidyant | Zendy; Kavita Kakkar | Zendy; Tapan N. Dhole | Zendy

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Chemokines and Chemokine Receptors in Susceptibility to HIV-1 Infection and Progression to AIDS

Author(s) -

Animesh Chatterjee,

Anurag S. Rathore,

Sanjukta Vidyant,

Kavita Kakkar,

Tapan N. Dhole

Publication year - 2012

Publication title -

disease markers

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.912

H-Index - 66

eISSN - 1875-8630

pISSN - 0278-0240

DOI - 10.1155/2012/147148

Subject(s) - chemokine receptor , chemokine receptor ccr5 , chemokine , immunology , biology , human immunodeficiency virus (hiv) , receptor , cxc chemokine receptors , c c chemokine receptor type 6 , ccr2 , virology , immune system , genetics

A multitude of host genetic factors plays a crucial role in susceptibility to HIV-1 infection and progression to AIDS, which is highly variable among individuals and populations. This review focuses on the chemokine-receptor and chemokine genes, which were extensively studied because of their role as HIV co-receptor or co-receptor competitor and influences the susceptibility to HIV-1 infection and progression to AIDS in HIV-1 infected individuals.

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