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Dedifferentiated Liposarcoma Arising in an Esophageal Polyp: A Case Report
Author(s) -
Jorge TorresMora,
Ann M. Moyer,
Mark Topazian,
Jeffrey A. Alexander,
TsungTeh Wu,
Amber R. Seys,
Karen Fritchie
Publication year - 2012
Publication title -
case reports in gastrointestinal medicine
Language(s) - English
Resource type - Journals
eISSN - 2090-6528
pISSN - 2090-6536
DOI - 10.1155/2012/141693
Subject(s) - liposarcoma , esophagus , medicine , fluorescence in situ hybridization , pathology , fish <actinopterygii> , anatomy , gene , sarcoma , biology , genetics , fishery , chromosome
Liposarcoma is one of the most common sarcomas in adults, but only rarely presents as an esophageal primary. There have been several reports of well-differentiated liposarcoma (WDL) arising in the esophagus, but we present a case of dedifferentiated liposarcoma (DL) presenting as a large esophageal polyp. We believe this is the first reported case of DL of the esophagus with morphologic evidence of both well-differentiated and dedifferentiated components. The diagnosis was confirmed by demonstration of CPM gene amplification by fluorescence in situ hybridization (FISH).

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