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Daptomycin-Nonsusceptible, Vancomycin-Intermediate, Methicillin-ResistantStaphylococcus aureusEndocarditis
Author(s) -
Ryan Yu,
Suzanne E. Dale,
Deborah Yamamura,
Vida Stankus,
Christine U. Lee
Publication year - 2012
Publication title -
canadian journal of infectious diseases and medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 38
eISSN - 1918-1493
pISSN - 1712-9532
DOI - 10.1155/2012/138470
Subject(s) - daptomycin , vancomycin , methicillin resistant staphylococcus aureus , staphylococcus aureus , microbiology and biotechnology , endocarditis , medicine , biology , bacteria , genetics
Due to the emergence of Staphylococcus aureus with reduced vancomycin susceptibility, newer antibiotics, including daptomycin, have been used to treat methicillin-resistant S aureus infections. Daptomycin is a cyclic lipopeptide that is approved to treat S aureus bacteremia and right-sided endocarditis, and reports of S aureus with reduced susceptibility to daptomycin are infrequent. To our knowledge, the present report describes the first Canadian case of daptomycin-nonsusceptible, vancomycin-intermediate S aureus infection.

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