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Objective . To assess the relationship between work productivity with disease activity, functional capacity, life quality and radiological damage in patients with rheumatoid arthritis (RA).  Methods . The study included consecutive employed patients with RA (ACR'87), aged over 18. Demographic, disease-related, and work-related variables were determined. The reduction of work productivity was assessed by WPAI-RA.  Results . 90 patients were evaluated, 71% women. Age average is 50 years old, DAS28 4, and RAQoL 12. Median SENS is 18 and HAQ-A 0.87. Mean absenteeism was of 14%, presenting an average of 6.30 work hours wasted weekly. The reduction in performance at work or assistance was of 38.4% and the waste of productivity was of 45%. Assistance correlated with DAS28 ( r  = 0.446;  P  < 0.001), HAQ-A ( r  = 0.545;  P  < 0.001) and RAQoL ( r  = 0.475;  P  < 0.001). Lower total productivity was noticed in higher levels of activity and functional disability. Patients with SENS > 18 showed lower work productivity than those with SENS < 18 (50 versus 34;  P  = 0.04). In multiple regression analysis, variables associated with reduction of total work productivity were HAQ-A and RAQoL.  Conclusion . RA patients with higher disease severity showed higher work productivity compromise.

Work Productivity in Rheumatoid Arthritis: Relationship with Clinical and Radiological Features