Open AccessOutcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only
Author(s) -
Jan J. Jobsen,
Lambert Naudin ten Cate,
Marnix L.M. Lybeert,
Astrid N. Scholten,
Elzbieta M. van der SteenBanasik,
Job van der Palen,
Marika C. Stenfert Kroese,
Annerie Slot,
Eltjo M.J. Schutter,
Sabine Siesling
Publication year - 2011
Publication title -
obstetrics and gynecology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.648
H-Index - 13
eISSN - 1687-9589
pISSN - 1687-9597
DOI - 10.1155/2011/962518
Subject(s) - medicine , endometrial cancer , stage (stratigraphy) , gynecology , oncology , general surgery , cancer , paleontology , biology
Objective . The aim of this study is to look at possible differences in outcome between serosa and adnexal involvement stage IIIA endometrial carcinoma. Methods . 67 patients with stage IIIA endometrial carcinoma were included, 46 with adnexal involvement and 21 with serosa. A central histopathological review was performed. Results . The 7-year locoregional failure rate was (LRFR) 2.2% for adnexal involvement and 16.0% for involvement of the serosa ( P = .0522). The 7-year distant metastasis-free survival was 72.7% for adnexal involvement and 58.7% for serosa ( P = .3994). The 7-year disease-specific survival (DSS) was 71.8% for patients with adnexal involvement and 75.4% for patients with serosa. Conclusion . Endometrial carcinoma stage IIIA with involvement of the adnexa or serosa showed to have a comparable disease-specific survival. Locoregional control was worse for serosa involvement compared to adnexa.
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